Answer by Chris McCray · Oct 06, 2010 at 12:49 PM
I'd add that make sure the driver letter that the external HDD is using is always the same. You can set this using the Disk Management leaf in the Windows Computer Management application tree. That way, any registry settings or other settings files that are stored on your operating system drive (usually drive C:) with explicit driver-letter references to your external HDD will always refer to the same drive.
I tend to start from the other end of the alphabet, and have drives Z and Y, for instance, though if you've had the drive available as (say) drive E: for a while, then just enforce that drive letter choice and you're done.
You could also mount the drive in a sub-folder on drive C:. Again you can do this from within the Disk Management leaf - same dialog box, just choose "Mount in the following NTFS folder" - your main OS drive (C:) needs to be NTFS to do this. This could be handy if the game detects the drive type and decides as it's an external drive, to not allow you to use it (I can't think of a game that does this, but if you find one, it's a potential workaround).
If you unplug the external HDD and plug it into a different USB port, your PC may think it's a different drive and assign it the same drive letter again. You may have to always plug it into the same USB port though (I'm presuming it's USB not Firewire or external-SATA, though this advice may hold for Firewire and multiple Firewire ports - I only have USB external HDDs so can't confirm).
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